StockWatch
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Biotechnology: Biological Products (No Diagnostic Substances)
PartnershipAug 11, 2026, 07:32 AM

C4 Therapeutics Secures Roche DAC Partnership with $20M Upfront, $1B+ Milestones

AI Summary

C4 Therapeutics announced a new collaboration and license agreement with Roche to develop degrader-antibody conjugates (DACs) for oncology targets. The agreement includes an upfront payment of $20.0 million and potential milestone payments exceeding $1.0 billion. For the six months ended June 30, 2026, the company reported a net loss of $48.8 million, an improvement from $52.3 million in the prior year period. C4 Therapeutics also confirmed its cash, cash equivalents, and marketable securities of $300.4 million are sufficient to fund operations for at least the next twelve months.

Key Highlights

  • Entered new collaboration with Roche for degrader-antibody conjugates (DACs).
  • Received $20.0 million upfront payment from Roche.
  • Eligible for over $1.0 billion in potential milestone payments from Roche.
  • Net loss for six months ended June 30, 2026, was $(48.8) million.
  • Net loss per share improved to $(0.38) for the six months.
  • Cash, cash equivalents, and marketable securities totaled $300.4 million.
  • Existing funds sufficient for at least the next 12 months of operations.