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Biotechnology: Pharmaceutical Preparations
Clinical TrialJul 16, 2026, 01:46 PM

Clearmind Medicine Reports Positive Retention Results for Intranasal MEAI

AI Summary

Clearmind Medicine Inc. announced positive ex vivo mucoadhesion results for its intranasal formulation of MEAI (5-Methoxy-2-aminoindane). The study demonstrated that the new formulation had significantly improved nasal residence characteristics compared to a standard MEAI solution. This enhanced nasal retention is considered a critical step for maximizing MEAI absorption and therapeutic potential, reinforcing the company's strategy for developing treatments for Alcohol Use Disorder (AUD) and other high-need indications.

Key Highlights

  • Clearmind Medicine reported positive ex vivo mucoadhesion results for its intranasal MEAI formulation.
  • The formulation demonstrated markedly improved nasal residence characteristics compared to a standard MEAI solution.
  • The study evaluated the ability of the formulation to remain associated with rabbit nasal tissue over a 30-minute period.
  • Intranasal MEAI consistently maintained a greater proportion of its initially adhered dose throughout the evaluation.
  • Enhanced nasal retention is a critical step toward maximizing MEAI absorption and therapeutic potential.
  • Results reinforce Clearmind's strategy for developing treatments for Alcohol Use Disorder (AUD) and other indications.
  • The study provides further validation of Clearmind’s nasal drug-delivery platform.