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Biotechnology: Biological Products (No Diagnostic Substances)
Quarterly ResultMay 4, 2026, 04:32 PM

CRISPR Therapeutics Q1 Net Loss $122.9M; CASGEVY Revenue $43M

AI Summary

CRISPR Therapeutics reported a net loss of $122.9 million for Q1 2026, an improvement from $136.0 million in Q1 2025. The company generated $43 million in revenue from CASGEVY, with over 500 patients globally initiating treatment. Key pipeline advancements include the expansion of zugo-cel into new autoimmune indications, FDA clearance for CTX310's U.S. trial, and regulatory submission for pediatric CASGEVY. The company's cash position strengthened to $2.44 billion, driven by $585.4 million from convertible senior notes.

Key Highlights

  • CASGEVY generated $43 million in Q1 2026 revenue.
  • Net loss for Q1 2026 was $122.9 million, down from $136.0 million YoY.
  • Cash, cash equivalents, and marketable securities totaled $2.44 billion.
  • Received $585.4 million from convertible senior notes in March 2026.
  • Over 500 people globally initiated CASGEVY treatment journey.
  • R&D expenses decreased to $68.6 million from $72.5 million YoY.
  • FDA cleared IND for CTX310, expanding trial into the U.S.
  • FDA cleared IND for zugo-cel in autoimmune neurologic diseases.
CRSP
Biotechnology: Biological Products (No Diagnostic Substances)
CRISPR Therapeutics AG

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