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Biotechnology: Pharmaceutical Preparations
AcquisitionsJun 5, 2026, 06:07 AM

Lakefront Biotherapeutics & Gilead Complete Ouro Medicines Acquisition

AI Summary

Gilead Sciences and Lakefront Biotherapeutics announced the successful completion of the acquisition of Ouro Medicines. This acquisition adds gamgertamig, a clinical-stage T cell engager for autoimmune diseases, to both companies' inflammation pipelines. Gilead acquired Ouro for $1,675 million upfront and up to $500 million in contingent milestone payments, which Lakefront will split equally with Gilead. Lakefront will collaborate on gamgertamig's development, receive tiered royalties on net sales, and has also in-licensed a preclinical portfolio from Ouro.

Key Highlights

  • Gilead Sciences and Lakefront Biotherapeutics completed the acquisition of Ouro Medicines.
  • Gilead acquired Ouro Medicines for $1,675 million upfront and up to $500 million in contingent milestone payments.
  • Lakefront and Gilead will equally split the upfront payment and contingent milestone payments.
  • Lakefront acquired Ouro's team and operational assets, collaborating with Gilead on gamgertamig development.
  • Lakefront will receive tiered royalties of 20%-23% on net sales of gamgertamig from Gilead.
  • Lakefront in-licensed a preclinical portfolio of three additional autoimmune programs from Ouro.
  • The transaction enables Lakefront to deploy at least $500 million independently, including up to $150 million for share buybacks.
  • Lakefront's year-end 2026 cash balance is expected to be approximately 2 billion.