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Biotechnology: Pharmaceutical Preparations
AcquisitionsMay 4, 2026, 08:49 AM

Gyre Therapeutics Closes $300M All-Stock Acquisition of Cullgen Inc.

AI Summary

Gyre Therapeutics, Inc. announced the closing of its all-stock acquisition of Cullgen Inc., valued at approximately $300 million. Following the transaction, Cullgen became a wholly owned subsidiary, and Dr. Ying Luo, former Cullgen CEO, was appointed President and Chief Executive Officer of Gyre. The combined entity now boasts a revenue-producing commercial asset, ETUARY®, and a robust pipeline focused on fibrosis and inflammatory diseases, including F351 which recently received priority review status in China.

Key Highlights

  • Gyre Therapeutics completed the all-stock acquisition of Cullgen Inc. for approximately $300 million.
  • Dr. Ying Luo, former Cullgen CEO, was appointed President and CEO of Gyre and joined the Board of Directors.
  • The combined entity will continue to be listed on the Nasdaq Capital Market under the ticker “GYRE”.
  • The new company offers a commercial-stage product, ETUARY®, on the market in China for lung fibrosis.
  • F351 (hydronidone) received priority review status from China’s NMPA for its NDA in March.
  • Enrollment completed in the 52-week Phase 3 ETUARY® trial for pneumoconiosis.
  • First patient enrolled in a Phase 3 study evaluating ETUARY® for radiation-induced lung injury.
  • Gyre Therapeutics owns a 69.7% equity interest in Gyre Pharmaceuticals as of December 31, 2025.
GYRE
Biotechnology: Pharmaceutical Preparations
GYRE THERAPEUTICS, INC.

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