StockWatch
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Biotechnology: Pharmaceutical Preparations
Quarterly ResultAug 4, 2026, 04:17 PM

OnKure Q2 Net Loss $15.3M; Cash $176.4M; INDs 1H 2027

AI Summary

OnKure Therapeutics reported its second quarter 2026 financial results, with a net loss of $15.3 million, or $0.31 per share. The company maintained a strong cash position of $176.4 million, expected to fund operations into 2029. OnKure continues to advance its PI3Kα pan-mutant selective inhibitor pipeline, with IND submissions for OKI-345 (breast cancer) and OKI-355 (vascular anomalies) on track for the first half of 2027.

Key Highlights

  • Cash, cash equivalents, and marketable securities totaled $176.4 million as of June 30, 2026.
  • Cash runway is expected to fund operations into 2029.
  • Net loss for Q2 2026 was $15.3 million, compared to $15.4 million for Q2 2025.
  • Net loss per share was $0.31 for Q2 2026, compared to $1.14 for Q2 2025.
  • Research and development expenses were $12.6 million for Q2 2026, flat year-over-year.
  • General and administrative expenses increased to $4.3 million for Q2 2026 from $3.7 million in Q2 2025.
  • IND submissions for OKI-345 and OKI-355 are planned for 1H 2027.