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Biotechnology: Biological Products (No Diagnostic Substances)
Quarterly ResultMay 12, 2026, 04:08 PM

Palisade Bio Q1 Net Loss $(9.6)M; Cash $132.6M

AI Summary

Palisade Bio reported a net loss of $(9.6) million for the first quarter of 2026, a significant increase from $(2.2) million in the prior year, driven by higher research and development and general and administrative expenses. Despite the increased loss, the company maintains a strong cash position of $132.6 million, providing sufficient capital for over a year of operations, largely due to a $127.6 million equity offering in October 2025. The Phase 2b study for ALTO-100 (formerly NSI-189) in major depressive disorder did not meet its primary endpoint, while the PALI-2108 program continues to advance with funding from the Crohn's & Colitis Foundation.

Key Highlights

  • Net loss for Q1 2026 was $(9.6) million, compared to $(2.2) million in Q1 2025.
  • Cash and cash equivalents totaled $132.6 million as of March 31, 2026.
  • Research and development expenses increased to $6.4 million from $0.95 million year-over-year.
  • General and administrative expenses rose to $4.4 million from $1.4 million year-over-year.
  • Net cash used in operating activities was $(3.9) million for the three months ended March 31, 2026.
  • Basic and diluted net loss per common share was $(0.05) for Q1 2026.
  • ALTO-100 Phase 2b study for major depressive disorder did not meet its primary endpoint.
  • Issued 1.54 million common shares for $3.0 million and 191,717 shares to CCF.
PALI
Biotechnology: Biological Products (No Diagnostic Substances)
PALISADE BIO, INC.

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