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Biotechnology: Pharmaceutical Preparations
Quarterly ResultMay 13, 2026, 08:07 AM

Tyra Biosciences Q1 Net Loss $39.3M; Dabogratinib Trials Advance

AI Summary

Tyra Biosciences reported its first quarter 2026 financial results, highlighting significant progress in its "dabogratinib 3x3" clinical strategy. The company announced a strong cash position of $383.5 million, providing a runway into the second half of 2028, bolstered by $147.9 million in net proceeds from an ATM offering. While net loss increased to $39.3 million, the company advanced its clinical trials, including dosing the first patient in the potentially registrational SURF303 study for LG-UTUC and anticipating multiple data readouts later this year for SURF302 and BEACH301.

Key Highlights

  • Cash, cash equivalents, and marketable securities totaled $383.5 million as of March 31, 2026.
  • Cash runway is expected to extend into the second half of 2028.
  • Net proceeds of $147.9 million were received from the at-the-market (ATM) offering program.
  • Research and Development (R&D) expenses increased to $33.5 million in Q1 2026 from $25.0 million in Q1 2025.
  • General and Administrative (G&A) expenses rose to $8.5 million in Q1 2026 from $6.9 million in Q1 2025.
  • Net loss for Q1 2026 was $39.3 million, compared to $28.1 million for Q1 2025.
  • First patient dosed in SURF303 (LG-UTUC) study, with initial results expected in 2027.
  • Initial Ph2 data from SURF302 (IR NMIBC) expected in August 2026 (n>20 enrolled).
  • Initial Ph2 data from BEACH301 (ACH) safety sentinel cohort expected in Q4 2026 (4th dose level cleared).
TYRA
Biotechnology: Pharmaceutical Preparations
Tyra Biosciences, Inc.

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