
Veradermics VDPHL01 Phase 2 trial positive; 22.7-23.3 hairs/cm² increase
Veradermics, Inc. announced positive topline data from its Phase 2 clinical trial, Study ‘207,’ evaluating VDPHL01 in females with mild-to-moderate pattern hair loss. The proprietary extended-release oral minoxidil formulation demonstrated significant hair growth, with an average increase of 22.7 to 23.3 hairs/cm² at Month 6, and 88.9% to 90.0% of participants reporting 'improved' or 'much improved' hair coverage. The drug was generally well-tolerated with no treatment-related serious adverse events, and showed rapid onset of activity as early as Month 2. These results strengthen conviction for the upcoming Phase 2/3 Study ‘306’ readout in 1H 2027, positioning VDPHL01 as a potential first FDA-approved oral treatment for female pattern hair loss.
Key Highlights
- VDPHL01 Phase 2 Study ‘207’ showed positive topline data in female pattern hair loss.
- Average non-vellus hair count increased by 22.7 hairs/cm² (QD) and 23.3 hairs/cm² (BID) at Month 6.
- 88.9% (QD) and 90.0% (BID) of participants reported 'improved' or 'much improved' hair coverage.
- Fast onset of hair growth observed as early as Month 2, with 63.2% of patients reporting improvement.
- VDPHL01 demonstrated a favorable safety profile with no treatment-related serious adverse events.
- Most common adverse events were hypertrichosis (21.4%) and peripheral edema (7.1%).
- Veradermics anticipates topline results for Phase 2/3 Study ‘306’ in 1H 2027.
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